The central laboratory was opened at the Medical University of Debrecen on January 1, 1978. It has served as the central diagnostics laboratory of the Clinical Center of the University of Debrecen Teaching Hospital since 2011 under the name Laboratory Medicine Institute (LMI). Clinical samples arrive at the lab 24 hours a day through a 8.6 km long underground, closed pneumatic tube system connecting the institute with all clinical units. Now, 4.5 million tests are made at the institute from 400 different types of lab tests and more than 50 of these are available 24/7. The laboratory provides unique profiles in the country in numerous specialized diagnostic fields for the examination of patients with the below listed areas being of great priority.
In the examination of leukemia and immunological disorders the flow cytometry division uses modern, 8-color panels for the examination of cell surface and intracellular markers, and it also provides an opportunity for the exact detection of specific rare receptor deficiencies, for example, paroxysmal nocturnal hemoglobinuria and Glanzmann’s thrombasthenia.
The diagnostics of congenital development disorders, mental disabilities, malignant hematological diseases are supported by cytogenetic testing, also providing an opportunity for the detection of cytogenetic and molecular genetic alterations behind infertility and habitual abortion.
Our separation methods help the diagnosis of catecholamine-secreting tumors and beta thalassemia. The endocrinological laboratory testing of heart, thyroid, parathyroid, adrenal glands, pancreas, growth and reproduction is also possible. The specification of drug levels includes carbamazepine and valproic acid used in the treatment of epilepsy, as well as different immunosuppressive preparations.
Besides the examination of platelet function disorders, detection of von Willebrand disease, hemorrhagic diatheses, we also perform the extensive diagnosis of thrombophilia. The comprehensive diagnostics of rare bleeding disorders should also be highlighted.
Methods in molecular biology make the exploration of the genetic background of severe inherited diseases possible, along with the detection of inherited risk factors, pharmacogenetic tests. They also help the diagnosis of oncological diseases and the study of markers of bone metabolism. The detection of serum tumor markers is carried out with immunochemical methods.